Oxidative Stress and Matrix Metalloproteinase-9 in Acute Ischemic Stroke
نویسندگان
چکیده
منابع مشابه
Oxidative stress and matrix metalloproteinase-9 in acute ischemic stroke: the Biomarker Evaluation for Antioxidant Therapies in Stroke (BEAT-Stroke) study.
BACKGROUND AND PURPOSE Experimental stroke studies indicate that oxidative stress is a major contributing factor to ischemic cerebral injury. Oxidative stress is also implicated in activation of matrix metalloproteinases (MMPs) and blood-brain barrier injury after ischemia-reperfusion. Plasma biomarkers of oxidative stress may have utility as early indicators of efficacy in Phase 2 trials of an...
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BACKGROUND The impact of serum matrix metalloproteinases-9 (MMP-9) on cognitive impairment after ischemic stroke is unclear. We aimed to investigate the association between serum MMP-9 in the short-term acute phase of ischemic stroke and cognitive impairment at 3 months. METHODS AND RESULTS Our study was based on a subsample from the CATIS (China Antihypertensive Trial in Acute Ischemic Strok...
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BACKGROUND AND PURPOSE Plasma matrix metalloproteinase-9 levels predict posttissue plasminogen activator (tPA) hemorrhage. METHODS The authors investigated the effect of minocycline on plasma matrix metalloproteinase-9 in acute ischemic stroke in the Minocycline to Improve Neurological Outcome in Stroke (MINOS) trial and a comparison group. RESULTS Matrix metalloproteinase-9 level decreased...
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Background: Meningioma is one of the most common tumors of the central nervous system. It was shown that meningioma had up-regulated expression of Matrix Metalloproteinases (MMPs) that involved in cell growth, angiogenesis and metastasis. Objectives: The aim of the study was the assessment of serum MMP-2 and -9 levels in patients with different grades of meningioma. Materials & Me...
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ژورنال
عنوان ژورنال: Stroke
سال: 2008
ISSN: 0039-2499,1524-4628
DOI: 10.1161/strokeaha.107.488189